By car
from Siena: Villa San Bartolomeo is about a 25-minute drive. Take the SS73 towards Asciano, then follow the signs for Castello di Leonina.
From Florence: Villa San Bartolomeo is about a 1 hour and 20-minute drive. Take the A1 motorway towards Rome, exit at Valdichiana, then follow the signs for Asciano and Castello di Leonina.